Loes Research Lab
About Us
We study the genetics of severe mental illness. Specifically, we aim to characterize and predict psychiatric disease trajectories using genetic and high-dimensional phenotypic data resources, such as electronic health records. We have a special focus on studying genetic and environmental risk factors that contribute to the cause and course of illness in admixed populations, in Colombia, Brazil and the USA. Through Misión Origen, we are creating a biobank for Severe Mental Illness, consisting of 100,000 participants from the Paisa region of Colombia.
We are a research group in the Center for Neurobehavioral Genetics in the Department of Psychiatry and Biobehavioral Sciences in the Semel Institute of the David Geffen School of Medicine at UCLA. We are also affiliated with the Departments of Human Genetics and Computational Medicine and the Bioinformatics, and Biomath PhD programs.
News
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New papers alert!! Accelerating the diagnosis of bipolar disorder
Our lab studies clinical and genetic markers to predict unipolar depression patients at risk for bipolar disorder. Check out our two new papers!
Loes Olde Loohuis was re-elected as chair of APN!
Loes has been re-elected as co-chair of the Ancestral Population Network (APN) together with Benjamin Neale!
Ana Maria presents at WCPG in Singapore!
We went to Singapore for the World Congress of Psychiatric Genetics (WCPG) and the Ancestral Population Network (APN) annual meeting.
Preprint: Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project)
We have released a preprint detailing our work on harmonizing psychiatric phenotypes for genetic analysis within the PUMAS project.