About Misión Origen

Latin American descended populations are poorly represented in psychiatric genetics research. Through Misión Origen, we are creating a biobank for Severe Mental Illness, consisting of 50,000 participants with severe mental illness and 50,000 population controls from the Paisa region of Colombia. All phenotyping will be through electronic medical records.

Co-led by Loes Olde Loohuis, Carlos Lopez Jaramillo, and Nelson Freimer. Funded by NIMH. For some of our ongoing work in this population, see: Service et al. 2020, Lancet Psychiatry and Mooney et al. 2018, American Journal of Human Genetics, Service et al. 2023, Song et al. 2024, De la Hoz et al 2022. 


Promotional Video

Website (in Spanish)

In this same population, we are studying the effect of the covid pandemic on patients with pre-existing SMI illness (RF1MH133426). Through longitudinal phenotyping of patients diagnosed with SMI pre-pandemic, using EHR and other clinical data, we aim to identify specific variables that may predict poor pandemic outcomes.


Mision Origen spanish website